MDMA, m\u1ed9t ch\u1ea5t \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn v\u1edbi t\u00e1c d\u1ee5ng g\u00e2y ph\u1ea5n kh\u00edch v\u00e0 t\u0103ng c\u01b0\u1eddng \u0111\u1ed3ng c\u1ea3m, \u0111ang thu h\u00fat s\u1ef1 quan t\u00e2m ng\u00e0y c\u00e0ng t\u0103ng trong l\u0129nh v\u1ef1c y t\u1ebf nh\u1edd ti\u1ec1m n\u0103ng tr\u1ecb li\u1ec7u c\u1ee7a n\u00f3. Khi \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng v\u1edbi li\u1ec1u l\u01b0\u1ee3ng ki\u1ec3m so\u00e1t, n\u00f3 c\u00f3 th\u1ec3 gi\u00fap \u0111\u1ee1 nh\u1eefng ng\u01b0\u1eddi m\u1eafc c\u00e1c r\u1ed1i lo\u1ea1n t\u00e2m l\u00fd li\u00ean quan \u0111\u1ebfn ch\u1ea5n th\u01b0\u01a1ng s\u00e2u s\u1eafc. C\u00e1c nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n tr\u00ean nh\u1eefng t\u00ecnh nguy\u1ec7n vi\u00ean kh\u1ecfe m\u1ea1nh cho th\u1ea5y MDMA, v\u1edbi li\u1ec1u l\u01b0\u1ee3ng t\u1eeb 75 \u0111\u1ebfn 125 miligam, gi\u00fap t\u0103ng c\u01b0\u1eddng t\u00e2m tr\u1ea1ng t\u00edch c\u1ef1c, s\u1ef1 \u0111\u1ed3ng c\u1ea3m, l\u00f2ng tin v\u00e0 c\u1ea3m x\u00fac h\u01b0\u1edbng v\u1ec1 x\u00e3 h\u1ed9i. Nh\u1eefng t\u00e1c d\u1ee5ng n\u00e0y li\u00ean quan \u0111\u1ebfn vi\u1ec7c gi\u1ea3i ph\u00f3ng t\u0103ng c\u01b0\u1eddng m\u1ed9t s\u1ed1 ch\u1ea5t d\u1eabn truy\u1ec1n h\u00f3a h\u1ecdc trong n\u00e3o, nh\u01b0 serotonin, dopamine v\u00e0 norepinephrine.<\/p>\n
Trong qu\u00e1 tr\u00ecnh t\u00e1c \u0111\u1ed9ng, MDMA t\u1ea1m th\u1eddi l\u00e0m thay \u0111\u1ed5i kh\u1ea3 n\u0103ng m\u00e3 h\u00f3a k\u00fd \u1ee9c m\u1edbi, \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 h\u1ed7 tr\u1ee3 qu\u00e1 tr\u00ecnh x\u1eed l\u00fd ch\u1ea5n th\u01b0\u01a1ng b\u1eb1ng c\u00e1ch gi\u1ea3m b\u1edbt s\u1ef1 s\u1ed1ng \u0111\u1ed9ng c\u1ee7a nh\u1eefng k\u00fd \u1ee9c ti\u00eau c\u1ef1c. Tuy nhi\u00ean, n\u00f3 kh\u00f4ng l\u00e0m cho c\u00e1 nh\u00e2n tr\u1edf n\u00ean d\u1ec5 b\u1ecb \u1ea3nh h\u01b0\u1edfng ho\u1eb7c d\u1ec5 b\u1ecb t\u1ed5n th\u01b0\u01a1ng tr\u01b0\u1edbc nh\u1eefng th\u00f4ng tin sai l\u1ec7ch. C\u00e1c ch\u1ee9c n\u0103ng \u0111i\u1ec1u h\u00e0nh, nh\u01b0 ki\u1ec3m so\u00e1t xung \u0111\u1ed9ng, v\u1eabn \u0111\u01b0\u1ee3c b\u1ea3o t\u1ed3n t\u1ed5ng th\u1ec3, m\u1eb7c d\u00f9 kh\u1ea3 n\u0103ng ph\u1ed1i h\u1ee3p v\u1eadn \u0111\u1ed9ng v\u00e0 t\u00ednh linh ho\u1ea1t nh\u1eadn th\u1ee9c c\u00f3 th\u1ec3 b\u1ecb gi\u1ea3m nh\u1eb9.<\/p>\n
Nh\u1eefng t\u00e1c d\u1ee5ng n\u00e0y thay \u0111\u1ed5i t\u00f9y theo chuy\u1ec3n h\u00f3a, ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch, t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u00e0 b\u1ed1i c\u1ea3nh s\u1eed d\u1ee5ng. Sau khi s\u1eed d\u1ee5ng, c\u00f3 th\u1ec3 x\u1ea3y ra t\u00ecnh tr\u1ea1ng gi\u1ea3m t\u00e2m tr\u1ea1ng v\u00e0 m\u1ec7t m\u1ecfi t\u1ea1m th\u1eddi, ph\u1ea3n \u00e1nh s\u1ef1 gi\u1ea3m t\u1ea1m th\u1eddi c\u1ee7a c\u00e1c ch\u1ea5t d\u1eabn truy\u1ec1n h\u00f3a h\u1ecdc trong n\u00e3o. Trong b\u1ed1i c\u1ea3nh tr\u1ecb li\u1ec7u, nh\u1eefng \u0111\u1eb7c t\u00ednh n\u00e0y c\u00f3 th\u1ec3 t\u0103ng c\u01b0\u1eddng m\u1ed1i quan h\u1ec7 gi\u1eefa b\u1ec7nh nh\u00e2n v\u00e0 nh\u00e0 tr\u1ecb li\u1ec7u, t\u1eeb \u0111\u00f3 th\u00fac \u0111\u1ea9y s\u1ef1 m\u1edf l\u00f2ng v\u00e0 ni\u1ec1m tin c\u1ea7n thi\u1ebft \u0111\u1ec3 \u0111\u1ed1i m\u1eb7t v\u1edbi nh\u1eefng k\u00fd \u1ee9c \u0111au \u0111\u1edbn.<\/p>\n
Tuy nhi\u00ean, vi\u1ec7c s\u1eed d\u1ee5ng MDMA trong tr\u1ecb li\u1ec7u \u0111\u00f2i h\u1ecfi s\u1ef1 gi\u00e1m s\u00e1t nghi\u00eam ng\u1eb7t. B\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 d\u1ec5 b\u1ecb l\u1ea1m d\u1ee5ng ho\u1eb7c ph\u1ee5 thu\u1ed9c v\u1ec1 m\u1eb7t c\u1ea3m x\u00fac do tr\u1ea1ng th\u00e1i \u00fd th\u1ee9c b\u1ecb thay \u0111\u1ed5i. Ngo\u00e0i ra, c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 m\u1ec7t m\u1ecfi ho\u1eb7c t\u00e2m tr\u1ea1ng tr\u1ea7m c\u1ea3m nh\u1eb9 sau khi s\u1eed d\u1ee5ng c\u1ea7n \u0111\u01b0\u1ee3c d\u1ef1 li\u1ec7u v\u00e0 qu\u1ea3n l\u00fd c\u1ea9n th\u1eadn.<\/p>\n
C\u00e1c nghi\u00ean c\u1ee9u c\u0169ng nh\u1ea5n m\u1ea1nh t\u1ea7m quan tr\u1ecdng c\u1ee7a vi\u1ec7c \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u l\u01b0\u1ee3ng d\u1ef1a tr\u00ean \u0111\u1eb7c \u0111i\u1ec3m c\u00e1 nh\u00e2n, nh\u01b0 gi\u1edbi t\u00ednh ho\u1eb7c y\u1ebfu t\u1ed1 di truy\u1ec1n, \u0111\u1ec3 t\u1ed1i \u0111a h\u00f3a l\u1ee3i \u00edch v\u00e0 gi\u1ea3m thi\u1ec3u r\u1ee7i ro. Cu\u1ed1i c\u00f9ng, vi\u1ec7c t\u00edch h\u1ee3p MDMA v\u00e0o c\u00e1c ph\u00e1c \u0111\u1ed3 tr\u1ecb li\u1ec7u c\u1ea7n \u0111\u01b0\u1ee3c quy \u0111\u1ecbnh b\u1edfi nh\u1eefng quy t\u1eafc nghi\u00eam ng\u1eb7t \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a li\u1ec7u ph\u00e1p.<\/p>\n
DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1038\/s41380-026-03602-7<\/a><\/p>\n Titre\u00a0:<\/strong> Subjective and neurocognitive profiling of clinical doses of 3,4-methylenedioxymethamphetamine (MDMA) in healthy volunteers: implications for therapeutic use<\/p>\n Revue : <\/strong> Molecular Psychiatry<\/p>\n \u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n Auteurs : <\/strong> Johannes G. Ramaekers; Kim P. C. Kuypers; Franz X. Vollenweider<\/p>\n","protected":false},"excerpt":{"rendered":" MDMA c\u00f3 th\u1ec3 bi\u1ebfn \u0111\u1ed5i li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb ch\u1ea5n th\u01b0\u01a1ng t\u00e2m l\u00fd? MDMA, m\u1ed9t ch\u1ea5t \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn v\u1edbi t\u00e1c d\u1ee5ng g\u00e2y ph\u1ea5n kh\u00edch v\u00e0 t\u0103ng c\u01b0\u1eddng \u0111\u1ed3ng c\u1ea3m, \u0111ang thu h\u00fat s\u1ef1 quan t\u00e2m ng\u00e0y c\u00e0ng t\u0103ng trong l\u0129nh v\u1ef1c y t\u1ebf nh\u1edd ti\u1ec1m n\u0103ng tr\u1ecb li\u1ec7u c\u1ee7a n\u00f3. Khi \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng… Continue reading MDMA c\u00f3 th\u1ec3 bi\u1ebfn \u0111\u1ed5i li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb ch\u1ea5n th\u01b0\u01a1ng t\u00e2m l\u00fd?<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,2],"tags":[],"class_list":["post-23","post","type-post","status-publish","format-standard","hentry","category-nhan-dao-con-nguoi","category-suc-khoe","entry"],"_links":{"self":[{"href":"https:\/\/psychiatryfoundation.com\/vi\/wp-json\/wp\/v2\/posts\/23","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/psychiatryfoundation.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/psychiatryfoundation.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/psychiatryfoundation.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/psychiatryfoundation.com\/vi\/wp-json\/wp\/v2\/comments?post=23"}],"version-history":[{"count":1,"href":"https:\/\/psychiatryfoundation.com\/vi\/wp-json\/wp\/v2\/posts\/23\/revisions"}],"predecessor-version":[{"id":24,"href":"https:\/\/psychiatryfoundation.com\/vi\/wp-json\/wp\/v2\/posts\/23\/revisions\/24"}],"wp:attachment":[{"href":"https:\/\/psychiatryfoundation.com\/vi\/wp-json\/wp\/v2\/media?parent=23"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/psychiatryfoundation.com\/vi\/wp-json\/wp\/v2\/categories?post=23"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/psychiatryfoundation.com\/vi\/wp-json\/wp\/v2\/tags?post=23"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}